All healthy individuals continuously produce cancer cells
throughout their lives. These cells occur on an ongoing basis
and because they develop from within the body, they are referred
to as autologous. Malignant cells result from the effects of
mutations and viruses and exposure to carcinogens ranging from
radiation or, tobacco smoke, to pesticides, and food colourings
and preservatives, just to mention a few.
It is the primary task of the cellular immune system to detect
these cancer cells early and destroy them. When cancer occurs,
the immune response is suppressed, or there has been an
excessive exposure to a carcinogen. Impaired immune function
often involves a drop in the number and/or the function of
immune cells available to effectively detect or kill cancer
cells.
Dendritic cells are one of the keys to an effective immune
response to cancerous cells. The dendritic cells migrate
throughout the tissues of the body, checking for abnormal cells.
Dendritic cells also target cells with the potential to become
malignant, due to chronic infection by a virus (for example a
chronic viral infection in the cervix such as human papilloma
virus (HPV) which can develop into a malignancy).
When an abnormal cell, such as a cancer cell, has been detected
the dendritic cell travels to a nearby lymph node and presents
the “ID” (the specific antigen profile) of the cancer cell to be
destroyed.
Researchers have shown that fresh and vital dendritic cells can
be introduced into the body in the form of a vaccine. If cancer
is present, inoculation with new dendritic cells alerts the
immune system to the presence of cancer and restarts proper
immune function. This serves to mobilize the exceptional power
of the immune system to identify cancer and combat it.
These dendritic cells are cultured from the patient’s own white
blood cells (so they are described as “autologous”). Initially,
after a simple blood draw, the blood is sent to a high-tech
medical laboratory where specially trained cell biologists and
technicians separate out certain white blood cells (monocytes)
from the blood. These cells are then cultured and transformed in
seven days into a new generation dendritic cells. This new
generation of vital, activated dendritic cells is re-introduced
into the patient’s body through simple intractaneous injections.
Dendritic cells are cultured from the patient’s own white blood
cells (so they are described as “autologous”). After a simple
blood draw, the blood is sent to a high-tech medical laboratory
where specially trained cell biologists and technicians separate
out certain white blood cells (monocytes) from the blood. These
cells are then cultured and transformed within seven days into a
new generation dendritic cells. This new generation of vital,
activated dendritic cells is re-introduced into the patient’s
body through simple intractaneous injections.
After the injection, Dendritic cells migrate throughout the
tissues of the body, checking for abnormal cells. Their role is
not only to detect where the cancer cells are located, but
Dendritic cells also target cells with the potential to become
malignant, due to chronic infection by a virus (for example a
chronic viral infection in the cervix such as human papilloma
virus (HPV) which can develop into a malignancy).
When an abnormal cell such as a cancer cell has been detected,
the dendritic cell travels to a nearby lymph node and presents
the “ID” (the specific antigen profile) of the cancer cell to be
destroyed.
The first step is to induce fever—either by total-body
hyperthermia or by localized hyperthermia—provided in
conjunction with the dendritic cell vaccine. Normally, fever is
initiated and controlled by certain centers in the brain stem,
which is also responsible for maintaining core body temperature.
Fever is the necessary condition that ramps up the entire immune
defence system, which is essential in eliminating diseases.
The second step is the dendritic cells vaccination, which
provides immune defences with the means to identify and target
the cancer cells to be destroyed. The injections are generally
well tolerated, with almost no side effects except for a fever
that typically starts the day of the injection and lasts 4 to 24
hours.